![This seed gives you D4 on the second item room. It lead to one of the funniest and most entertaining runs I've had yet. (Keep the D4 through the entire run for This seed gives you D4 on the second item room. It lead to one of the funniest and most entertaining runs I've had yet. (Keep the D4 through the entire run for](https://external-preview.redd.it/hYAy_pOkEQFME4S5zj33kNgjjlT0p5KVyvzZoTXYN7w.jpg?auto=webp&s=2061253981650eede5dbbe0772073cff70528cc8)
This seed gives you D4 on the second item room. It lead to one of the funniest and most entertaining runs I've had yet. (Keep the D4 through the entire run for
![When the D4 treats you just right by Alili1996 | Pacha Edits / When The Sun Hits That Ridge Just Right | Know Your Meme When the D4 treats you just right by Alili1996 | Pacha Edits / When The Sun Hits That Ridge Just Right | Know Your Meme](https://i.kym-cdn.com/photos/images/original/001/075/830/ed3.png)
When the D4 treats you just right by Alili1996 | Pacha Edits / When The Sun Hits That Ridge Just Right | Know Your Meme
![Infestation - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game. Infestation - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game.](https://i0.wp.com/foursoulsspoiler.net/wp-content/uploads/plus2-infestation.png?w=500&ssl=1)
Infestation - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game.
![🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: The D4! this is one of a few "one use items" that destroys itself and does something epic. in this case it "rerolls" all items 🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: The D4! this is one of a few "one use items" that destroys itself and does something epic. in this case it "rerolls" all items](https://pbs.twimg.com/media/Diva6A_UEAA-xlq.png)
🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: The D4! this is one of a few "one use items" that destroys itself and does something epic. in this case it "rerolls" all items
![Tyrone Rodriguez ( ○ ︿○) on Twitter: "The Lost will start with Spectral Tears + D4 AFTER we release Isaac Rebirth on Wii U, new 3DS and Xbox One #beefcake http://t.co/8ojCJ1j4Ay" / Twitter Tyrone Rodriguez ( ○ ︿○) on Twitter: "The Lost will start with Spectral Tears + D4 AFTER we release Isaac Rebirth on Wii U, new 3DS and Xbox One #beefcake http://t.co/8ojCJ1j4Ay" / Twitter](https://pbs.twimg.com/media/CExy6m3UsAAADZc.png)
Tyrone Rodriguez ( ○ ︿○) on Twitter: "The Lost will start with Spectral Tears + D4 AFTER we release Isaac Rebirth on Wii U, new 3DS and Xbox One #beefcake http://t.co/8ojCJ1j4Ay" / Twitter
![MÖRK CY_BORG on Twitter: "Monster time! MÖRK BORG's art guy Johan is a big fan of the roguelike video game The Binding of Isaac by @edmundmcmillen, and statted six of its monsters MÖRK CY_BORG on Twitter: "Monster time! MÖRK BORG's art guy Johan is a big fan of the roguelike video game The Binding of Isaac by @edmundmcmillen, and statted six of its monsters](https://pbs.twimg.com/media/ETj2jzAXkAAZMZJ.jpg:large)